medical device
PSORIN
dedicated for patients with psoriasis
medical device
PSORIN gel
for daily use on the scalp affected by psoriasis
Softens the scales and helps to remove them. Soothes irritations and itching. Regular use helps prevent the intensification of psoriatic symptoms and prolongs the remission time.
SOOTHES IRRITATIONS
relieves pain and burning sensations caused by skin lesions
SOFTENS AND HELPS TO REMOVE THE SCALES
moisturises the skin and has a keratolytic effect
DOES NOT CONTAIN PRESERVATIVES, COLOURS OR FRAGRANCES
safe to use and specially made for those suffering from psoriasis
CLINICALLY PROVEN TO BE EFFECTIVE
a dermatological study carried out on a group of patients with psoriasis confirmed the effectiveness
Ingredients:
Pale Ichthyol, Sodium Hyaluronate, D-Panthenol, Allantoin, Glycerin, Carbomer, Phenylethyl Alcohol, Caprylyl Glycol, Purified Water, Triethanolamine.
Pale Ichthyol
contributes to the normalization of the epidermis exfoliation process and relieves itching and irritation
Allantoin, d-panthenol and sodium hyaluronate
create a protective layer on the skin and maintain its proper hydration
A dermatological study carried out on a group of patients with psoriasis confirmed the effectiveness of PSORIN gel. Patients participating in the study were between 18 to 60 years old. Patients used PSORIN medical devices for a period of 4 weeks. Subsequently, the test results were analysed and the following was observed:
- easing of itching and burning,
- reduction in skin irritation,
- moisturising of the skin,
- assistance in scales removal,
- extended remission time.
medical device
PSORIN lotion
for daily use on the affected skin in the treatment of psoriasis. It normalises the process of exfoliation of the epidermis, helping to remove the scales. It has an antipruritic effect, soothes irritations whilst moisturising and lubricating the skin.
REDUCES THE BURNING SENSATION
SOFTENS, IMPROVES ELASTICITY AND IS EASILY ABSORBED
DOES NOT CONTAIN SLS, PARABENS, COLOURS
Ingredients:
Pale Ichthyol, D-Panthenol, Allantoin, Glycerin, Isopropyl myristate, Caprylic/capric triglyceride, Cetearyl alcohol, Cetomacrogol 1000, Cetostearyl glucoside, Dimethicone, Purified water, Phenoxyethanol.
medical device
PSORIN
cream
for daily use on affected skin in the treatment of psoriasis. It normalises the process of exfoliation of the epidermis, removing the scales formed as a result of the disease. It has an antipruritic effect, soothes irritations and the burning sensation whilst moisturising and lubricating the skin.
SOOTHES IRRITATIONS
creates a protective layer on the skin
HAS A UNIQUE COMPOSITION
contains licorice extract to effectively moisturise and nourish the skin
PREVENTS WORSENING OF SYMPTOMS
extends the remission time of the disease
Ingredients:
Pale Ichthyol, Bees wax, Liquid paraffin, White petrolatum, Dry extract of licorice root (20% glycyrrhizic acid), Cetearyl alcohol, Cetomacrogol 1000, Glycerol stearate, Purified water, Phenoxyethanol.
What is psoriasis?
Psoriasis is one of the chronic immune-mediated inflammatory diseases (IMIDs) that affects the skin. Its aetiology remains unknown. The prevalence of psoriasis varies depending on geographical factors, race or ethnic origin, and affects about 2% of the world population; 1–3% of the population of Europe and the United States.
Along with atopic dermatitis, psoriasis is one of the most common dermatological diseases. Psoriasis is a recurrent disease, characterised by periods of exacerbation and remission. The disease can lead to disability once it starts affecting joints and to premature death (due to the development of complications associated with the metabolic syndrome, which commonly accompanies psoriasis). Persistent generalised inflammation in the patient’s body, known as “psoriatic march”, leads to the activation of many inflammatory cytokines, which may indirectly lead to changes in the cardiovascular system, arterial hypertension, metabolic disorders, diabetes, non-alcoholic fatty liver disease, and many other comorbidities. Psoriasis can be associated with depression, even with suicidal thoughts, all caused by a lack of acceptance of one’s appearance, and a feeling of shame, anxiety and stigmatization.
What are the symptoms of psoriasis?
The skin undergoes continuous regeneration by exfoliating the outer layer of dead cells and revealing new, fresh epidermal cells underneath them. In a healthy person, this process takes about a month, but in patients who have psoriasis, this takes 3-4 days. As a result of the accumulation of rapidly maturing cells, rough red patches form on the surface of the skin, which are covered with thick, silvery-white scales.
Diagnosis of psoriasis is usually based on the assessment of morphology of the skin lesions and the location of the scales. These most commonly appear on: elbows, knees, the lumbosacral region of the back, buttocks, skin of the feet and hands, as well as the scalp. If there are doubts to the clinical diagnosis, a skin biopsy from the affected area and histopathological verification are recommended. In the initial stage of the disease, skin lesions appear as lumps clearly demarcated from the surrounding skin. At the site of the lesions, the skin is itchy and red. The lesions can also be painful. The severity of symptoms varies: from cases where the skin hardly changes, to severe forms of the disease, characterised by inflammatory and exudative changes, often taking a generalised form (erythrodermic psoriasis).
The disease usually has a genetic basis. The disease commonly manifests itself in two age groups: those between 16 and 22 years of age, and those between 57 and 60 years of age. Psoriasis can also appear in childhood. It is estimated that approximately 30-50% of adults with psoriasis developed the disease before the age of 20.
What are the causes of psoriasis?
The aetiology of psoriasis is not fully known. Genetic, immunological and environmental factors are key in the development of the disease. Although the development of psoriasis is determined by genetic predisposition, the disease is not inherited directly. The predispositions are inherited from the parents, and may or may not manifest themselves at some point in the lifetime once environmental factors come in to play.
It has been proven that if one parent has psoriasis, there is a 25% risk of their offspring inheriting the disease. The risk is significantly higher (from 60 to 70%) if both parents have psoriasis. The disease is immune-related, and it is correlated with the malfunctioning of the cells of the immune system. This process quickly gets out of control and leads to extensive inflammation. The environmental factors that affect morbidity include climatic conditions such as sun exposure.Research has shown that the prevalence of psoriasis depends on geographic factors, as well as race and ethnicity. The condition is most often diagnosed among White ethnic group (2% of population affected), less commonly in Asians, and rarely in Black population. There is a predominance in a number of cases in Europe and North America, and it is much less common in Asia and Africa. Certain factors can cause the disease and worsen the symptoms. These include: stress, infections, cold and dry weather, skin injuries (cuts, scratches, insect bites or severe sunburn), smoking or exposure to passive smoking, excessive alcohol consumption, and obesity. There is also „Koebner phenomenon”, which is the appearance of psoriatic lesions 6-12 days after scratching the epidermis. Koebner phenomenon can only appear in active psoriasis. It cannot be induced in remission state. Psoriasis can also be caused by piercings, tattooing, sunburn and exposure to chemical irritants.
Psoriasis skin treatment
Psoriasis skin should be treated with the utmost care and requires the use of appropriately selected and combined preparations, with appropriate ingredients corresponding to patient’s needs. Treatment with specially dedicated products not only eases symptoms, but also improves the patient’s well-being. The basis of treatment is systematic, effective moisturising and lubrication with pharmaceutical preparations which support medical treatment. Patients should use preparations with safe ingredients that have a soothing effect and promote the healing of inflamed skin.
THANKS TO THE UNIQUE COMBINATION OF ITS ACTIVE INGREDIENTS, THE PSORIN SERIES OF MEDICAL DEVICES IS A SAFE AND EFFECTIVE THERAPY FOR PEOPLE AFFECTED BY PSORIASIS.
The active ingredients in the Psorin series
The key active substance in the PSORIN medical devices series is Pale Ichthyol. It is an active substance of natural origin with a particularly wide spectrum of pharmacological activity. As a result of special processing, two separate fractions of shale oil are obtained – pale sulfonated shale oil (Pale Ichthyol) and dark sulfonated shale oil. Pale Ichthyol is contained in the fraction with a lower boiling point – it is lighter and has a less distinctive odour. It is equally effective at a lower concentration, which means its use is more favorable than of the dark oil. Pale Ichthyol does not cause irritations and can be used without risk by all age groups. It has anti-inflammatory, antibacterial, antipruritic, anti-seborrheic, analgesic, keratolytic, anti-mitotic properties and helps heal wounds. Pale Ichthyol exhibits mycostatic, antiseptic and anti-inflammatory properties similar to those found in hydrocortisone. This is probably due to modulating the inflammatory response by lowering the levels of local infection markers. As it is used in conditions of excessive flaking of the skin, its anti-proliferative effect is also of benefit.
Recent research has led to the development of further treatment options for patients with skin conditions. However, this expansion is not without its flaws. Modern drugs and procedures are an effective way of getting the disease under control, but they are expensive and can lead to toxic effects in patients. The substances that were previously used can still result in effective and safe treatment of common dermatological diseases and therefore their use should be reconsidered.
The advantage of pale ichthyol over coal tar, dithranol and even over calcipotriol, is the lack of irritating, phototoxic and carcinogenic potential. Furthermore, ichthyol reduces erythema and hypersensitivity to UVB radiation. In many countries, dermatological centres use it for the treatment of psoriasis in combination with NB-UVB phototherapy. The test results confirmed the effectiveness (after 20 sessions: the average PASI reduction = 72%, the average DLQI improvement = 53%), tolerance and safety of this type of therapy in the treatment of severe cases of the disease, and even among patients with guttate psoriasis, seborrheic psoriasis, erythrodermic psoriasis and those who were paediatrics. Another advantage is the fact that it is easily washed out with water and is much cheaper compared to other drugs. Due to its anti-inflammatory properties, nourishing and cleansing, pale ichthyol can also be used in the treatment of seborrheic dermatitis and dandruff.
At the start of the treatment of psoriatic lesions, it is recommended to use keratolytic agents to remove the build-up of scales that hinder the penetration of psoriasis medication deep into the lesions, thereby reducing their effectiveness. The substance that exhibits keratolytic properties is allantoin (0.2% allantoin solution displays similar efficacy to 10% urea solution). Allantoin increases the ability of the stratum corneum to bind water and help relieve symptoms of dry skin, such as burning or the sensation of the skin feeling tight. Allantoin accelerates proliferation of epithelial cells, thanks to this the skin regenerates faster and more efficiently rebuilds the protective hydrolipid coat. Sodium hyaluronate also has a beneficial effect on the skin, which, due to its properties, creates a layer on the surface of the skin that protects against water loss and adverse external factors.
The licorice extract is high in healing properties due to the presence of triterpene saponins, flavonoids, coumarins and polysaccharides. The main ingredient of licorice extract is glycyrrhizinic acid, which along with other chemical compounds derived from this plant has anti-inflammatory, antibacterial and moisturising properties. Research has shown that licorice-based products are as effective in reducing skin inflammations as hydrocortisone acetate 1%.
Other highly moisturising natural substances present in the PSORIN series include:
- yellow beeswax, containing palmitic acid, which creates a delicate layer that prevents drying. The squalene contained in the wax complements the natural hydro-lipid barrier of the epidermis and has an antiseptic effect. The carotenoids which are also present in the beeswax have antioxidant properties. All of the above illustrate to what extent the wax helps in the treatment of skin diseases.
- D-panthenol acts as a humectant, retaining water in the stratum corneum. This ensures effective moisturising of the skin and helps to soften the scales and relieve other symptoms of psoriasis such as redness and pruritus.
Given that over the last few years there has been a significant increase in the number of patients with dermatoses looking for alternative treatments following post-targeted treatment, PSORIN series effectively provides for this.
Contact
Responsible entity:
-
FARMINA SP. Z O.O.
UL. LIPSKA 44
30-721 KRAKÓW
POLAND - info@farmina.pl
- +48 12 290 90 00
- +48 12 290 90 50
- www.farmina.pl
- Do you want to partner with us?
- international@farminagroup.com
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